SpA Lab.Collaborate

SpA Research AI Laboratory

An autonomous
AI lab studying
axial SpA.

We use AI agents to investigate axial spondyloarthritis: how it works, what may change its course, and where better treatments could come from.

An independent laboratory bringing human direction and computational research together.

Explore the lab model Our work
The research loop
From a question to research that can be inspectedA conceptual research cycle links a question, investigation, analysis and critical review, and a report. Evidence and project records connect the stages. Ask a questionInvestigateAnalyse& challengeShare findings A sharedresearchrecord.SOURCES · METHODS · CODE
A model of the workflow, not a live activity monitor.
SpA Lab — Autonomous AI Research Laboratory. A helix with vertebra-shaped rungs.The vision

Understand the disease more deeply.
Help make better treatment possible.

01 / What we investigate

One disease.
Connected questions.

Our focus is axial spondyloarthritis. We investigate the existing evidence and develop computational questions that can lead to useful, testable research.

01

Disease mechanisms

What can biological and clinical data reveal about the processes that drive the disease—and the connections between them?

02

Interventions & daily life

What evidence supports treatments, diet, exercise and other everyday practices, and which outcomes do they actually change?

03

Progression & repair

How do we distinguish reduced inflammation, prevention of new damage and possible repair of existing structural changes?

These are research directions. Specific questions, completed studies and their limitations live in Our work ↗.

02 / How the lab is organized

Human direction.
AI-led investigation.

Pawel sets the broad goals. Astra turns them into a research programme and coordinates the work.

Focused agents take on investigation, analysis and critical review as tasks require. Saved protocols, evidence and code give the laboratory continuity between sessions.

How the process works
01

Human direction

Pawel Kuklik

Founder · research priorities and broad direction.

Human
02

AI coordination

GPT-6 Astra

Project planning, task delegation, integration and progress reporting.

AI
03

Focused research tasks

Investigate · analyse · review

AI roles assigned to bounded work, with source records and checks.

AI
↗

Collaborators sought

Clinical & experimental expertise

Human specialists for independent scrutiny and future laboratory validation.

03 / Research in the open

Follow the questions.
Inspect the work.

Our project library brings together completed research, readable summaries, methods and data.

SpA Lab is at an early stage. We are developing autonomy through bounded research projects, with explicit limits and a growing record of work others can inspect.

Explore our work